Cool-Season Vegetable

When to Plant Lettuce in Missouri

Fast-growing and forgiving. Plant in spring and fall for a nearly year-round supply of fresh salad greens.

The Short Answer

Lettuce are cold-tolerant and do well in Missouri's humid climate. You can direct sow 4 weeks before your last frost — that's as early as Apr 20 - May 5 in Northern Missouri. Missouri gardeners can also plant a fall crop. Rich loess soils along Missouri River. Rocky Ozark soils in south. Heavy clay common. Generally...

Missouri Frost Dates

Your planting dates depend on which part of Missouri you're in. Here are the frost date ranges by region:

Region Zones Last Frost (Spring) First Frost (Fall)
Northern Missouri 5b, 6a Apr 20 - May 5 Oct 1 - Oct 15
Central Missouri 6a, 6b Apr 10 - Apr 25 Oct 10 - Oct 25
Southern Missouri 6b, 7a Apr 1 - Apr 15 Oct 15 - Nov 1

Lettuce Planting Schedule for Missouri

Northern Missouri (Zones 5b, 6a)

Average last frost: Apr 20 - May 5 · Average first frost: Oct 1 - Oct 15

Start Seeds Indoors
4 wks before frost
Transplant Outside
2 wks before frost
Direct Sow
4 wks before frost
Fall Planting
8 wks before first frost

Central Missouri (Zones 6a, 6b)

Average last frost: Apr 10 - Apr 25 · Average first frost: Oct 10 - Oct 25

Start Seeds Indoors
4 wks before frost
Transplant Outside
2 wks before frost
Direct Sow
4 wks before frost
Fall Planting
8 wks before first frost

Southern Missouri (Zones 6b, 7a)

Average last frost: Apr 1 - Apr 15 · Average first frost: Oct 15 - Nov 1

Start Seeds Indoors
4 wks before frost
Transplant Outside
2 wks before frost
Direct Sow
4 wks before frost
Fall Planting
8 wks before first frost

Growing Lettuce in Missouri

Lettuce in Missouri's Climate

Lettuce grows well in spring and fall but bolts when summer temperatures consistently exceed 80°F. Direct sow 4 weeks before your last frost and succession plant every 2 weeks until mid-May. Resume in August for fall harvest. Summer lettuce is possible with heat-tolerant varieties and afternoon shade, but expect shorter-lived plantings.

Soil Considerations for Missouri

Rich loess soils along Missouri River. Rocky Ozark soils in south. Heavy clay common. Generally fertile.

Missouri Climate & Growing Season

Continental climate. Hot, humid summers. Four seasons. Good growing season in most of state.

Growing season length varies across Missouri: Northern Missouri (5b, 6a) has a last frost around Apr 20 - May 5, while Southern Missouri (6b, 7a) sees frost end around Apr 1 - Apr 15. This difference matters for lettuce — adjust your planting dates to match your specific region.

Growing Tips

Succession plant every 2-3 weeks for continuous harvest. Shade cloth extends the season into warmer months.

Companion Planting

Plant lettuce alongside these companions for better growth:

Carrots Radishes Strawberries Chives

The Bottom Line

Lettuce can be grown successfully across Missouri, but your exact planting dates depend on which region you're in. Northern Missouri gardeners should plan around a Apr 20 - May 5 last frost, while those in Southern Missouri can typically plant earlier. For exact dates based on your zip code, use our free planting date finder.
Note: All dates are based on NOAA 30-year Climate Normals and represent historical averages, not predictions for any specific year. Always check your local weather forecast before planting frost-sensitive crops. Learn about our data sources.

Last reviewed: March 29, 2026

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